Epstein-Barr Virus-Negative Lymphoproliferative Disorders after Liver Transplantation
نویسندگان
چکیده
Lymphoproliferative disorders following liver transplantation are often Epstein-Barr virus (EBV)-related highgrade B cell lymphomas. EBV-negative and low-grade lymphoma is a very rare condition after cadaveric as well as living donor liver transplantation (LDLT). Herein we report a case of follicular lymphoma with negative EBV viral capsid antigen (VCA), IgM, IgG and Epstein-Barr virus-encoded small RNA (EBER), which developed after LDLT, and review the literature pertaining to EBV-negative post-transplantation lymphoproliferative disorder (PTLD) after liver transplantation.
منابع مشابه
Hepatitis C virus infection can affect lymphoproliferative disorders only as a cofactor for Epstein-Barr virus in liver transplant recipients: PTLD.Int survey.
OBJECTIVES Hepatitis C virus infection has a 10.5% frequency in liver transplant posttransplant lymphoproliferative disorders. Studies have suggested that hepatitis C virus infection plays a role in developing posttransplant lymphoproliferative disorders. Pooling data of posttransplant lymphoproliferative disorders developing in liver recipients from the literature, we analyzed and compared cha...
متن کاملPost-transplantation lymphoproliferative disorder with gastrointestinal involvement
Post-transplantation lymphoproliferative disorders (PTLDs) are lymphoid proliferations or lymphomas that are the second most common tumors in adult transplant recipients. Most cases of PTLD are attributed to Epstein-Barr virus, which induces B-cell proliferation and occurs in the setting of severe immunosuppression after solid organ or bone marrow transplantation. The disorder is seen in 1-3% o...
متن کاملesteban Frauca, et al.: Cytomegalovirus and Epstein-Barr Virus Infection in Pediatric Liver Transplants
Cytomegalovirus and Epstein-Barr virus infections remain one of the main concerns in the postoperative care of children with a liver transplantation. Most of the pediatric liver transplant recipients are seronegative for cytomegalovirus and/or Epstein-Barr virus at transplantation and this places them at marked risk for the development of cytomegalovirus/Epstein-Barr virus-related diseases. In ...
متن کاملPosttransplantation lymphoproliferative disorder involving liver after renal transplantation
Posttransplantation lymphoproliferative disorder (PTLD) is a serious complication following solid organ transplantation. Most of PTLD is related to an interaction of Epstein-Barr virus (EBV) infection and immune suppression. PTLD occurs most common after intestine transplantation and the least common after renal transplantation. PTLD can involve any organs. Abdominal organs are frequently invol...
متن کاملEpstein-Barr virus infection and central nervous system involvement after orthoptic liver transplant.
Epstein-Barr virus (EBV) infection presenting as encephalitis in seronegative adults in the context of solid organ transplantation is rarely reported. EBV seroconversion illnesses in the adult population after organ transplantation are quite uncommon. This report describes a case of encephalitis due to EBV infection after liver transplantation in an adult patient. The patient was seronegative f...
متن کامل